A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity

Cytoplasmic dynein is the major minus-end-directed microtubule-based motor in cells. Dynein processivity and cargo selectivity depend on cargo-specific effectors that, while generally unrelated, share the ability to interact with dynein and dynactin to form processive dynein–dynactin-effector comple...

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Detalles Bibliográficos
Autores principales: Lee, In-Gyun, Olenick, Mara A., Boczkowska, Malgorzata, Franzini-Armstrong, Clara, Holzbaur, Erika L. F., Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841405/
https://www.ncbi.nlm.nih.gov/pubmed/29515126
http://dx.doi.org/10.1038/s41467-018-03412-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841405/
https://www.ncbi.nlm.nih.gov/pubmed/29515126
http://dx.doi.org/10.1038/s41467-018-03412-8

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