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A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity
Cytoplasmic dynein is the major minus-end-directed microtubule-based motor in cells. Dynein processivity and cargo selectivity depend on cargo-specific effectors that, while generally unrelated, share the ability to interact with dynein and dynactin to form processive dynein–dynactin-effector comple...
Autores principales: | Lee, In-Gyun, Olenick, Mara A., Boczkowska, Malgorzata, Franzini-Armstrong, Clara, Holzbaur, Erika L. F., Dominguez, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841405/ https://www.ncbi.nlm.nih.gov/pubmed/29515126 http://dx.doi.org/10.1038/s41467-018-03412-8 |
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