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Down-regulation of GADD45A enhances chemosensitivity in melanoma

Melanoma is a malignant skin cancer with considerable drug resistance. Increased expression of DNA repair genes have been reported in melanoma, and this contributes to chemotherapy resistance. GADD45A is involved in DNA repair, cell cycle arrest and apoptosis in response to physiologic or environmen...

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Detalles Bibliográficos
Autores principales:	Liu, Jia, Jiang, Guoqiang, Mao, Ping, Zhang, Jing, Zhang, Lin, Liu, Likun, Wang, Jia, Owusu, Lawrence, Ren, Baoyin, Tang, Yawei, Li, Weiling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841426/ https://www.ncbi.nlm.nih.gov/pubmed/29515153 http://dx.doi.org/10.1038/s41598-018-22484-6

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