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Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow – A proof of concept study

Diagnostic and prognostic evaluation of chronic lymphocytic leukemia (CLL) involves blood cell counts, immunophenotyping, IgVH mutation status, and cytogenetic analyses. We generated B-cell associated gene-signatures (BAGS) based on six naturally occurring B-cell subsets within normal bone marrow. O...

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Detalles Bibliográficos
Autores principales:	Nørgaard, Caroline Holm, Jakobsen, Lasse Hjort, Gentles, Andrew J., Dybkær, Karen, El-Galaly, Tarec Christoffer, Bødker, Julie Støve, Schmitz, Alexander, Johansen, Preben, Herold, Tobias, Spiekermann, Karsten, Brown, Jennifer R., Klitgaard, Josephine L., Johnsen, Hans Erik, Bøgsted, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841735/ https://www.ncbi.nlm.nih.gov/pubmed/29513759 http://dx.doi.org/10.1371/journal.pone.0193249

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