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Microenvironmental cues enhance mesenchymal stem cell-mediated immunomodulation and regulatory T-cell expansion
Mesenchymal stem cells (MSCs) are known to both have powerful immunosuppressive properties and promote allograft tolerance. Determining the environmental oxygen tension and inflammatory conditions under which MSCs are optimally primed for this immunosuppressive function is essential to their utiliza...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841747/ https://www.ncbi.nlm.nih.gov/pubmed/29513756 http://dx.doi.org/10.1371/journal.pone.0193178 |