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Microenvironmental cues enhance mesenchymal stem cell-mediated immunomodulation and regulatory T-cell expansion

Mesenchymal stem cells (MSCs) are known to both have powerful immunosuppressive properties and promote allograft tolerance. Determining the environmental oxygen tension and inflammatory conditions under which MSCs are optimally primed for this immunosuppressive function is essential to their utiliza...

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Detalles Bibliográficos
Autores principales: Kadle, Rohini L., Abdou, Salma A., Villarreal-Ponce, Alvaro P., Soares, Marc A., Sultan, Darren L., David, Joshua A., Massie, Jonathan, Rifkin, William J., Rabbani, Piul, Ceradini, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841747/
https://www.ncbi.nlm.nih.gov/pubmed/29513756
http://dx.doi.org/10.1371/journal.pone.0193178