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Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life

BACKGROUND: The placenta is the central regulator of maternal and fetal interactions. Perturbations of placental structure and function have been associated with adverse neurodevelopmental outcomes later in life. Placental CpG methylation represents an epigenetic modification with the potential to i...

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Detalles Bibliográficos
Autores principales: Tilley, Sloane K., Martin, Elizabeth M., Smeester, Lisa, Joseph, Robert M., Kuban, Karl C. K., Heeren, Tim C., Dammann, Olaf U., O’Shea, T. Michael, Fry, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841757/
https://www.ncbi.nlm.nih.gov/pubmed/29513726
http://dx.doi.org/10.1371/journal.pone.0193271

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