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An anti-PDGFRβ aptamer for selective delivery of small therapeutic peptide to cardiac cells

Small therapeutic peptides represent a promising field for the treatment of pathologies such as cardiac diseases. However, the lack of proper target-selective carriers hampers their translation towards a potential clinical application. Aptamers are cell-specific carriers that bind with high affinity...

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Detalles Bibliográficos
Autores principales: Romanelli, Alessandra, Affinito, Alessandra, Avitabile, Concetta, Catuogno, Silvia, Ceriotti, Paola, Iaboni, Margherita, Modica, Jessica, Condorelli, Geroloma, Catalucci, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841773/
https://www.ncbi.nlm.nih.gov/pubmed/29513717
http://dx.doi.org/10.1371/journal.pone.0193392