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Assessment of the immunogenicity of residual host cell protein impurities of OsrHSA
Human serum albumin (HSA) is the most abundant protein in human plasma and is widely used at high doses for treating various diseases. Recombinant HSA is an alternative approach to plasma-derived HSA, providing increased safety and an unlimited supply. However, the safety of the residual host cell p...
Autores principales: | Abiri, Naghmeh, Pang, Jianlei, Ou, Jiquan, Shi, Bo, Wang, Xianghong, Zhang, Sucai, Sun, Yunxia, Yang, Daichang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841786/ https://www.ncbi.nlm.nih.gov/pubmed/29513721 http://dx.doi.org/10.1371/journal.pone.0193339 |
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