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Deep sequencing of HBV pre-S region reveals high heterogeneity of HBV genotypes and associations of word pattern frequencies with HCC
Hepatitis B virus (HBV) infection is a common problem in the world, especially in China. More than 60–80% of hepatocellular carcinoma (HCC) cases can be attributed to HBV infection in high HBV prevalent regions. Although traditional Sanger sequencing has been extensively used to investigate HBV sequ...
Autores principales: | Bai, Xin, Jia, Jian-an, Fang, Meng, Chen, Shipeng, Liang, Xiaotao, Zhu, Shanfeng, Zhang, Shuqin, Feng, Jianfeng, Sun, Fengzhu, Gao, Chunfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841821/ https://www.ncbi.nlm.nih.gov/pubmed/29474353 http://dx.doi.org/10.1371/journal.pgen.1007206 |
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