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Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2

Fibroblasts persist within fibrotic scar tissue and exhibit considerable phenotypic and functional plasticity. Herein, we hypothesized that scar-associated fibroblasts may be a source of stress-induced inflammatory exacerbations and pain. To test this idea, we used a human model of surgery-induced f...

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Detalles Bibliográficos
Autores principales:	Paish, Hannah L., Kalson, Nicholas S., Smith, Graham R., del Carpio Pons, Alicia, Baldock, Thomas E., Smith, Nicholas, Swist-Szulik, Katarzyna, Weir, David J., Bardgett, Michelle, Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Investigative Pathology 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842035/ https://www.ncbi.nlm.nih.gov/pubmed/29248462 http://dx.doi.org/10.1016/j.ajpath.2017.11.007

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