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Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation
Burkholderia pseudomallei is an environmental bacterium that causes melioidosis, a major community-acquired infection in tropical regions. Melioidosis presents with a range of clinical symptoms, is often characterized by a robust inflammatory response, may relapse after treatment, and results in hig...
Autores principales: | Sengyee, Sineenart, Yoon, Sung Hwan, Paksanont, Suporn, Yimthin, Thatcha, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, West, T. Eoin, Ernst, Robert K., Chantratita, Narisara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842036/ https://www.ncbi.nlm.nih.gov/pubmed/29474381 http://dx.doi.org/10.1371/journal.pntd.0006287 |
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