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Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment

PURPOSE: Systemic increases in reactive oxygen species, and their association with inflammation, have been proposed as an underlying mechanism linking obesity and age-related macular degeneration (AMD). Studies have found increased levels of oxidative stress biomarkers and inflammatory cytokines in...

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Detalles Bibliográficos
Autores principales: Natoli, Riccardo, Fernando, Nilisha, Dahlenburg, Tess, Jiao, Haihan, Aggio-Bruce, Riemke, Barnett, Nigel L., Chao de la Barca, Juan Manuel, Tcherkez, Guillaume, Reynier, Pascal, Fang, Johnny, Chu-Tan, Joshua A., Valter, Krisztina, Provis, Jan, Rutar, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842320/
https://www.ncbi.nlm.nih.gov/pubmed/29527116