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Secretion of Legumain Increases in Conditioned Medium from DJ-1-Knockout Cells and in Serum from DJ-1-Knockout Mice

BACKGROUND: Asparaginyl endopeptidase, also known as legumain (EC 3.4.22.34) shows strong activity in the mouse kidney. Legumain is also highly expressed in tumors. DJ-1/PARK7 is a Parkinson’s disease- and cancer-associated protein. DJ-1 is a coactivator of various transcription factors. Recently, w...

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Detalles Bibliográficos
Autores principales:	Yamane, Takuya, Kato-Ose, Izumi, Sakamoto, Tatsuji, Nakano, Yoshihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2018
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842380/ https://www.ncbi.nlm.nih.gov/pubmed/29541256 http://dx.doi.org/10.2174/1874091X01812010029

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