17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes

Prolactin (PRL) and estrogen cooperate in lobuloalveolar development of the mammary gland and jointly regulate gene expression in breast cancer cells in vitro. Canonical PRL signaling activates STAT5A/B, homologous proteins that have different target genes and functions. Although STAT5A/B are import...

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Detalles Bibliográficos
Autores principales: Jallow, Fatou, Brockman, Jennifer L, Helzer, Kyle T, Rugowski, Debra E, Goffin, Vincent, Alarid, Elaine T, Schuler, Linda A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842396/
https://www.ncbi.nlm.nih.gov/pubmed/29594259
http://dx.doi.org/10.1210/js.2017-00399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842396/
https://www.ncbi.nlm.nih.gov/pubmed/29594259
http://dx.doi.org/10.1210/js.2017-00399

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