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17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes
Prolactin (PRL) and estrogen cooperate in lobuloalveolar development of the mammary gland and jointly regulate gene expression in breast cancer cells in vitro. Canonical PRL signaling activates STAT5A/B, homologous proteins that have different target genes and functions. Although STAT5A/B are import...
Autores principales: | Jallow, Fatou, Brockman, Jennifer L, Helzer, Kyle T, Rugowski, Debra E, Goffin, Vincent, Alarid, Elaine T, Schuler, Linda A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842396/ https://www.ncbi.nlm.nih.gov/pubmed/29594259 http://dx.doi.org/10.1210/js.2017-00399 |
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