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Chondroitin Sulfate Impairs Neural Stem Cell Migration Through ROCK Activation
Brain injuries such as trauma and stroke lead to glial scar formation by reactive astrocytes which produce and secret axonal outgrowth inhibitors. Chondroitin sulfate proteoglycans (CSPG) constitute a well-known class of extracellular matrix molecules produced at the glial scar and cause growth cone...
Autores principales: | Galindo, Layla T., Mundim, Mayara T. V. V., Pinto, Agnes S., Chiarantin, Gabrielly M. D., Almeida, Maíra E. S., Lamers, Marcelo L., Horwitz, Alan R., Santos, Marinilce F., Porcionatto, Marimelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842503/ https://www.ncbi.nlm.nih.gov/pubmed/28477140 http://dx.doi.org/10.1007/s12035-017-0565-8 |
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