Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32

Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Accumulating evidences suggest that PD might have a strong neurodevelopmental component. Among the genetic cases, mutations in the leucine-rich repeat kinase 2 (LRRK2) are well known to be disease causing. Although the mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalez-Cano, Laura, Menzl, Ingeborg, Tisserand, Johan, Nicklas, Sarah, Schwamborn, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842508/
https://www.ncbi.nlm.nih.gov/pubmed/28508149
http://dx.doi.org/10.1007/s12035-017-0570-y

Ejemplares similares

Ejemplares similares