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Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations

BACKGROUND: Angiogenesis is a process of formation of new blood vessels and is an important criteria demonstrated by cancer cells. Over a period of time, these cancer cells infect the other parts of the healthy body by a process called progression. The objective of the present article is to identify...

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Detalles Bibliográficos
Autores principales:	Rampogu, Shailima, Baek, Ayoung, Zeb, Amir, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842552/ https://www.ncbi.nlm.nih.gov/pubmed/29514608 http://dx.doi.org/10.1186/s12885-018-4050-1

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