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The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor

BACKGROUND: Neuroinflammation is one of the hallmarks of neurodegenerative diseases, such as Parkinson’s disease (PD). Activation of glial cells, including microglia and astrocytes, is a characteristic of the inflammatory response. Glycoprotein non-metastatic melanoma protein B (GPNMB) is a transmem...

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Detalles Bibliográficos
Autores principales:	Neal, Matthew L., Boyle, Alexa M., Budge, Kevin M., Safadi, Fayez F., Richardson, Jason R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842560/ https://www.ncbi.nlm.nih.gov/pubmed/29519253 http://dx.doi.org/10.1186/s12974-018-1100-1

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