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The use of whole exome sequencing and murine patient derived xenografts as a method of chemosensitivity testing in sarcoma

BACKGROUND: Soft tissue and bone sarcoma represent a broad spectrum of different pathology and genetic variance. Current chemotherapy regimens are derived from randomised trials and represent empirical treatment. Chemosensitivity testing and whole exome sequencing (WES) may offer personalized chemot...

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Detalles Bibliográficos
Autores principales:	Calvert, Nicholas, Wu, Jiansha, Sneddon, Sophie, Woodhouse, Jennifer, Carey-Smith, Richard, Wood, David, Ingley, Evan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842605/ https://www.ncbi.nlm.nih.gov/pubmed/29541442 http://dx.doi.org/10.1186/s13569-018-0090-1

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