Cargando…

Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

BACKGROUND: Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD. METHODS: A genome-wide DNA methylation profile of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Yan, Li, Ping, Hao, Jingcan, Duan, Chen, Han, Jing, He, Awen, Du, Yanan, Liu, Li, Liang, Xiao, Zhang, Feng, Guo, Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842623/ https://www.ncbi.nlm.nih.gov/pubmed/29514696 http://dx.doi.org/10.1186/s13075-018-1531-1

Ejemplares similares

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis
por: Wu, Wenhong, et al.
Publicado: (2017)

Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease
por: Hao, Jingcan, et al.
Publicado: (2017)

A bivariate genome-wide association study identifies ADAM12 as a novel susceptibility gene for Kashin-Beck disease
por: Hao, Jingcan, et al.
Publicado: (2016)

Identifying discriminative features for diagnosis of Kashin-Beck disease among adolescents
por: Zhang, Yanan, et al.
Publicado: (2021)

Prevalence of hand osteoarthritis and knee osteoarthritis in Kashin-Beck disease endemic areas and non Kashin-Beck disease endemic areas: A status survey
por: Lian, Wei, et al.
Publicado: (2018)

Genome-Wide Differentially Methylated Region Analysis to Reveal Epigenetic Differences of Articular Cartilage in Kashin–Beck Disease and Osteoarthritis
por: Fan, Yue, et al.
Publicado: (2021)

Kashin-Beck disease involving the ankles
por: Niebulski, Hannah Z., et al.
Publicado: (2015)

Arthroscopic Ankle Arthrodesis for Treating Osteoarthritis in a Patient with Kashin-Beck Disease
por: Iwasa, Kenjiro, et al.
Publicado: (2014)

Alterations in the gut microbiota and metabolite profiles of patients with Kashin-Beck disease, an endemic osteoarthritis in China
por: Wang, Xi, et al.
Publicado: (2021)

Proteoglycan metabolism, cell death and Kashin-Beck Disease
por: Li, Siyuan, et al.
Publicado: (2012)

ATAC-seq reveals the roles of chromatin accessibility in the chondrocytes of Kashin–Beck disease compared with primary osteoarthritis
por: Wang, Sen, et al.
Publicado: (2023)

The expression of p-ATF2 involved in the chondeocytes apoptosis of an endemic osteoarthritis, Kashin-Beck disease
por: Han, Jing, et al.
Publicado: (2013)

Detection of selenoprotein transcriptome in chondrocytes of patients with Kashin–Beck disease
por: Gong, Yi, et al.
Publicado: (2023)

Growth surveillance indices and Kashin-Beck Disease in children
por: 马玮娟 (Ma Wei Juan),
Publicado: (2022)

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China
por: Ning, Yujie, et al.
Publicado: (2022)

Pathway-based network analyses and candidate genes associated with Kashin-Beck disease
por: Zhang, Rongqiang, et al.
Publicado: (2019)

Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis
por: Yang, Lei, et al.
Publicado: (2022)

Roles of glycoprotein glycosylation in the pathogenesis of an endemic osteoarthritis, Kashin–Beck disease, and effectiveness evaluation of sodium hyaluronate treatment
por: WANG, Sen, et al.
Publicado: (2020)

Differential gene expression in articular cartilage between rheumatoid arthritis and endemic Kashin–Beck disease
por: Gao, Zongqiang, et al.
Publicado: (2019)

WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway
por: Li, Ping, et al.
Publicado: (2023)

A study on atypical Kashin–Beck disease: an endemic ankle arthritis
por: Qi, Fang, et al.
Publicado: (2023)

Whole-Exome Sequencing for the Identification of Susceptibility Genes of Kashin–Beck Disease
por: Yang, Zhenxing, et al.
Publicado: (2014)

Genome-Wide Gene Expression Analysis Suggests an Important Role of Hypoxia in the Pathogenesis of Endemic Osteochondropathy Kashin-Beck Disease
por: Zhang, Feng, et al.
Publicado: (2011)

Genome-Wide Gene Expression Analysis Suggests an Important Role of Suppressed Immunity in Pathogenesis of Kashin-Beck Disease
por: Wang, Shuang, et al.
Publicado: (2012)

Abnormal expression of chondroitin sulphate N-acetylgalactosaminyltransferase 1 and Hapln-1 in cartilage with Kashin–Beck disease and primary osteoarthritis
por: Zheng, Jingjing, et al.
Publicado: (2013)

Proteomic analysis of knee cartilage reveals potential signaling pathways in pathological mechanism of Kashin-Beck disease compared with osteoarthritis
por: Lei, Jian, et al.
Publicado: (2020)

Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis
por: Wang, Xi, et al.
Publicado: (2021)

The role of humic substances in drinking water in Kashin-Beck disease in China.
por: Peng, A, et al.
Publicado: (1999)

Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis
por: Qi, Fang, et al.
Publicado: (2023)

Total hip replacement in adult patients with severe Kashin-Beck disease of the hip
por: Tang, Xin, et al.
Publicado: (2016)

Genetic variants in the ITPR2 gene are associated with Kashin‐Beck Disease in Tibetan
por: He, Xue, et al.
Publicado: (2019)

Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin–Beck disease
por: Yang, Lei, et al.
Publicado: (2020)

Identified molecular mechanism of interaction between environmental risk factors and differential expression genes in cartilage of Kashin–Beck disease
por: Yu, Fang-Fang, et al.
Publicado: (2016)

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China
por: Fang, Hua, et al.
Publicado: (2016)

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease
por: Ma, Mei, et al.
Publicado: (2020)

Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease
por: Lian, Wei, et al.
Publicado: (2018)

Combined Proximal Tibial Osteotomy for Adult Kashin–Beck Disease with Severe Varus Knee Osteoarthritis: Case Report and Literature Review
por: Liu, Yunfei, et al.
Publicado: (2022)

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease
por: Zhang, Feng, et al.
Publicado: (2012)

Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China?
por: Ning, Yujie, et al.
Publicado: (2015)

Association study of candidate genes for susceptibility to Kashin-Beck disease in a Tibetan population
por: Tai, Zhengfu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mrehf4jq0c6u14ogtc9evv6qbl