Cargando…

Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications

BACKGROUND: The objective of this study was to evaluate and identify the risk factors for developing a new or enlarged intracranial hemorrhage (ICH) after the placement of an external ventricular drain. METHODS: A single center, nested case-control study of individuals who received an external ventr...

Descripción completa

Detalles Bibliográficos
Autores principales: Rowe, A. Shaun, Rinehart, Derrick R., Lezatte, Stephanie, Langdon, J. Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842631/
https://www.ncbi.nlm.nih.gov/pubmed/29514640
http://dx.doi.org/10.1186/s12883-018-1030-7
_version_ 1783304939097817088
author Rowe, A. Shaun
Rinehart, Derrick R.
Lezatte, Stephanie
Langdon, J. Russell
author_facet Rowe, A. Shaun
Rinehart, Derrick R.
Lezatte, Stephanie
Langdon, J. Russell
author_sort Rowe, A. Shaun
collection PubMed
description BACKGROUND: The objective of this study was to evaluate and identify the risk factors for developing a new or enlarged intracranial hemorrhage (ICH) after the placement of an external ventricular drain. METHODS: A single center, nested case-control study of individuals who received an external ventricular drain from June 1, 2011 to June 30, 2014 was conducted at a large academic medical center. A bivariate analysis was conducted to compare those individuals who experienced a post-procedural intracranial hemorrhage to those who did not experience a new bleed. The variables identified as having a p-value less than 0.15 in the bivariate analysis were then evaluated using a multivariate logistic regression model. RESULTS: Twenty-seven of the eighty-one study participants experienced a new or enlarged intracranial hemorrhage after the placement of an external ventricular drain. Of these twenty-seven patients, 6 individuals received an antiplatelet within ninety-six hours of external ventricular drain placement (p = 0.024). The multivariate logistic regression model identified antiplatelet use within 96 h of external ventricular drain insertion as an independent risk factor for post-EVD ICH (OR 13.1; 95% CI 1.95–88.6; p = 0.008). CONCLUSION: Compared to those study participants who did not receive an antiplatelet within 96 h of external ventricular drain placement, those participants who did receive an antiplatelet were 13.1 times more likely to exhibit a new or enlarged intracranial hemorrhage.
format Online
Article
Text
id pubmed-5842631
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-58426312018-03-14 Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications Rowe, A. Shaun Rinehart, Derrick R. Lezatte, Stephanie Langdon, J. Russell BMC Neurol Research Article BACKGROUND: The objective of this study was to evaluate and identify the risk factors for developing a new or enlarged intracranial hemorrhage (ICH) after the placement of an external ventricular drain. METHODS: A single center, nested case-control study of individuals who received an external ventricular drain from June 1, 2011 to June 30, 2014 was conducted at a large academic medical center. A bivariate analysis was conducted to compare those individuals who experienced a post-procedural intracranial hemorrhage to those who did not experience a new bleed. The variables identified as having a p-value less than 0.15 in the bivariate analysis were then evaluated using a multivariate logistic regression model. RESULTS: Twenty-seven of the eighty-one study participants experienced a new or enlarged intracranial hemorrhage after the placement of an external ventricular drain. Of these twenty-seven patients, 6 individuals received an antiplatelet within ninety-six hours of external ventricular drain placement (p = 0.024). The multivariate logistic regression model identified antiplatelet use within 96 h of external ventricular drain insertion as an independent risk factor for post-EVD ICH (OR 13.1; 95% CI 1.95–88.6; p = 0.008). CONCLUSION: Compared to those study participants who did not receive an antiplatelet within 96 h of external ventricular drain placement, those participants who did receive an antiplatelet were 13.1 times more likely to exhibit a new or enlarged intracranial hemorrhage. BioMed Central 2018-03-07 /pmc/articles/PMC5842631/ /pubmed/29514640 http://dx.doi.org/10.1186/s12883-018-1030-7 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Rowe, A. Shaun
Rinehart, Derrick R.
Lezatte, Stephanie
Langdon, J. Russell
Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title_full Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title_fullStr Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title_full_unstemmed Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title_short Intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
title_sort intracerebral hemorrhage after external ventricular drain placement: an evaluation of risk factors for post-procedural hemorrhagic complications
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842631/
https://www.ncbi.nlm.nih.gov/pubmed/29514640
http://dx.doi.org/10.1186/s12883-018-1030-7
work_keys_str_mv AT roweashaun intracerebralhemorrhageafterexternalventriculardrainplacementanevaluationofriskfactorsforpostproceduralhemorrhagiccomplications
AT rinehartderrickr intracerebralhemorrhageafterexternalventriculardrainplacementanevaluationofriskfactorsforpostproceduralhemorrhagiccomplications
AT lezattestephanie intracerebralhemorrhageafterexternalventriculardrainplacementanevaluationofriskfactorsforpostproceduralhemorrhagiccomplications
AT langdonjrussell intracerebralhemorrhageafterexternalventriculardrainplacementanevaluationofriskfactorsforpostproceduralhemorrhagiccomplications