Cargando…
Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype
BACKGROUND: Smoking is the main risk factor for chronic obstructive pulmonary disease (COPD). Women with COPD who smoke experienced a higher risk of hospitalization and worse decline of lung function. Yet the mechanisms of these gender-related differences in clinical presentations in COPD remain unk...
Autores principales: | Yang, Mingxing, Kohler, Maxie, Heyder, Tina, Forsslund, Helena, Garberg, Hilde K., Karimi, Reza, Grunewald, Johan, Berven, Frode S., Nyrén, Sven, Magnus Sköld, C., Wheelock, Åsa M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842633/ https://www.ncbi.nlm.nih.gov/pubmed/29514663 http://dx.doi.org/10.1186/s12931-017-0699-2 |
Ejemplares similares
-
Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD
por: Yang, Mingxing, et al.
Publicado: (2018) -
Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD
por: Naz, Shama, et al.
Publicado: (2019) -
Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes
por: Forsslund, Helena, et al.
Publicado: (2016) -
Lung density on high resolution computer tomography (HRCT) reflects degree of inflammation in smokers
por: Karimi, Reza, et al.
Publicado: (2014) -
miRNA–mRNA–protein dysregulated network in COPD in women
por: Li, Chuan Xing, et al.
Publicado: (2022)