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Contribution of diacylglycerol lipase β to pain after surgery

BACKGROUND: Metabolism of the endocannabinoid 2-arachidonoylglycerol (2-AG) yields arachidonic acid (AA), the precursor to proalgesic eicosanoids including prostaglandin E2 (PGE(2)). Diacylglycerol lipase β (DAGLβ) is an enzyme that synthesizes 2-AG and its inhibition reduces eicosanoid levels and p...

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Detalles Bibliográficos
Autores principales:	Luk, Jennifer, Lu, Yong, Ackermann, Amanda, Peng, Xiaoxue, Bogdan, Diane, Puopolo, Michelino, Komatsu, David E, Tong, Simon, Ojima, Iwao, Rebecchi, Mario J, Kaczocha, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842774/ https://www.ncbi.nlm.nih.gov/pubmed/29551907 http://dx.doi.org/10.2147/JPR.S157208

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