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Actinic cheilitis: proposition and reproducibility of a clinical criterion

OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seem...

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Autores principales: Poitevin, Nádia Antunes, Rodrigues, Mariana Sudati, Weigert, Karen Loureiro, Macedo, Carmen Lúcia Rodrigues, dos Santos, Rubem Beraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842833/
https://www.ncbi.nlm.nih.gov/pubmed/29607086
http://dx.doi.org/10.1038/bdjopen.2017.16
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author Poitevin, Nádia Antunes
Rodrigues, Mariana Sudati
Weigert, Karen Loureiro
Macedo, Carmen Lúcia Rodrigues
dos Santos, Rubem Beraldo
author_facet Poitevin, Nádia Antunes
Rodrigues, Mariana Sudati
Weigert, Karen Loureiro
Macedo, Carmen Lúcia Rodrigues
dos Santos, Rubem Beraldo
author_sort Poitevin, Nádia Antunes
collection PubMed
description OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility. MATERIALS AND METHODS: Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18–74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI). RESULTS: During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed k=0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (k=0.779; P<0.05) and very good (k=0.925; P<0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (k=0.812; P<0.05 to k=0.925; P<0.05). DISCUSSION: Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student. CONCLUSIONS: The authors concluded that the proposed classification was easily applied and had a very good reproducibility.
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spelling pubmed-58428332018-03-30 Actinic cheilitis: proposition and reproducibility of a clinical criterion Poitevin, Nádia Antunes Rodrigues, Mariana Sudati Weigert, Karen Loureiro Macedo, Carmen Lúcia Rodrigues dos Santos, Rubem Beraldo BDJ Open Article OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility. MATERIALS AND METHODS: Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18–74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI). RESULTS: During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed k=0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (k=0.779; P<0.05) and very good (k=0.925; P<0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (k=0.812; P<0.05 to k=0.925; P<0.05). DISCUSSION: Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student. CONCLUSIONS: The authors concluded that the proposed classification was easily applied and had a very good reproducibility. Nature Publishing Group 2017-08-04 /pmc/articles/PMC5842833/ /pubmed/29607086 http://dx.doi.org/10.1038/bdjopen.2017.16 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Poitevin, Nádia Antunes
Rodrigues, Mariana Sudati
Weigert, Karen Loureiro
Macedo, Carmen Lúcia Rodrigues
dos Santos, Rubem Beraldo
Actinic cheilitis: proposition and reproducibility of a clinical criterion
title Actinic cheilitis: proposition and reproducibility of a clinical criterion
title_full Actinic cheilitis: proposition and reproducibility of a clinical criterion
title_fullStr Actinic cheilitis: proposition and reproducibility of a clinical criterion
title_full_unstemmed Actinic cheilitis: proposition and reproducibility of a clinical criterion
title_short Actinic cheilitis: proposition and reproducibility of a clinical criterion
title_sort actinic cheilitis: proposition and reproducibility of a clinical criterion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842833/
https://www.ncbi.nlm.nih.gov/pubmed/29607086
http://dx.doi.org/10.1038/bdjopen.2017.16
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