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Actinic cheilitis: proposition and reproducibility of a clinical criterion
OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seem...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842833/ https://www.ncbi.nlm.nih.gov/pubmed/29607086 http://dx.doi.org/10.1038/bdjopen.2017.16 |
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author | Poitevin, Nádia Antunes Rodrigues, Mariana Sudati Weigert, Karen Loureiro Macedo, Carmen Lúcia Rodrigues dos Santos, Rubem Beraldo |
author_facet | Poitevin, Nádia Antunes Rodrigues, Mariana Sudati Weigert, Karen Loureiro Macedo, Carmen Lúcia Rodrigues dos Santos, Rubem Beraldo |
author_sort | Poitevin, Nádia Antunes |
collection | PubMed |
description | OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility. MATERIALS AND METHODS: Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18–74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI). RESULTS: During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed k=0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (k=0.779; P<0.05) and very good (k=0.925; P<0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (k=0.812; P<0.05 to k=0.925; P<0.05). DISCUSSION: Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student. CONCLUSIONS: The authors concluded that the proposed classification was easily applied and had a very good reproducibility. |
format | Online Article Text |
id | pubmed-5842833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-58428332018-03-30 Actinic cheilitis: proposition and reproducibility of a clinical criterion Poitevin, Nádia Antunes Rodrigues, Mariana Sudati Weigert, Karen Loureiro Macedo, Carmen Lúcia Rodrigues dos Santos, Rubem Beraldo BDJ Open Article OBJECTIVES/AIMS: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip’s skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility. MATERIALS AND METHODS: Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18–74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI). RESULTS: During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed k=0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (k=0.779; P<0.05) and very good (k=0.925; P<0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (k=0.812; P<0.05 to k=0.925; P<0.05). DISCUSSION: Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student. CONCLUSIONS: The authors concluded that the proposed classification was easily applied and had a very good reproducibility. Nature Publishing Group 2017-08-04 /pmc/articles/PMC5842833/ /pubmed/29607086 http://dx.doi.org/10.1038/bdjopen.2017.16 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Poitevin, Nádia Antunes Rodrigues, Mariana Sudati Weigert, Karen Loureiro Macedo, Carmen Lúcia Rodrigues dos Santos, Rubem Beraldo Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title | Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title_full | Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title_fullStr | Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title_full_unstemmed | Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title_short | Actinic cheilitis: proposition and reproducibility of a clinical criterion |
title_sort | actinic cheilitis: proposition and reproducibility of a clinical criterion |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842833/ https://www.ncbi.nlm.nih.gov/pubmed/29607086 http://dx.doi.org/10.1038/bdjopen.2017.16 |
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