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Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination
Testis determination in mammals is initiated by expression of SRY in somatic cells of the embryonic gonad. Genetic analyses in the mouse have revealed a requirement for mitogen-activated protein kinase (MAPK) signaling in testis determination: targeted loss of the kinases MAP3K4 and p38 MAPK causes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842889/ https://www.ncbi.nlm.nih.gov/pubmed/27009039 http://dx.doi.org/10.1095/biolreprod.115.138057 |