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Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation and is required for maintaining transcriptional patterns and cellular identity, but the specification and maintenance of genomic PRC2 binding and H3K27 methylation patterns remain incompletely understood. Epigenetic mechanisms have...

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Detalles Bibliográficos
Autores principales:	Højfeldt, Jonas W, Laugesen, Anne, Willumsen, Berthe M, Damhofer, Helene, Hedehus, Lin, Tvardovskiy, Andrey, Mohammad, Faizaan, Jensen, Ole N, Helin, Kristian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842896/ https://www.ncbi.nlm.nih.gov/pubmed/29483650 http://dx.doi.org/10.1038/s41594-018-0036-6

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