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Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells

BACKGROUND: Albumin, as a major urinary protein component, is a risk factor for chronic kidney disease progression. Mitochondrial dysfunction is one of the main causes of albumin-induced proximal tubule cells injury. Mitophagy is considered as a pivotal protective mechanism for the elimination of dy...

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Detalles Bibliográficos
Autores principales: Tan, Jin, Xie, Qi, Song, Shuling, Miao, Yuyang, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843022/
https://www.ncbi.nlm.nih.gov/pubmed/29494565
http://dx.doi.org/10.12659/MSM.907718