Icotinib hydrochloride enhances chemo- and radiosensitivity by inhibiting EGFR signaling and attenuating RAD51 expression and function in Hela S3 cells

BACKGROUND: Radiotherapy and cisplatin-based chemotherapy are currently considered as standard treatments employed for advanced cervical cancer (CC). However, patients with local recurrence or distant metastasis continue to have poor outcomes. EGFR overexpression correlated with chemo/radioresistanc...

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Detalles Bibliográficos
Autores principales: Wang, Xuanxuan, Gu, Yanjun, Liu, Hai, Shi, Liming, Sun, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843137/
https://www.ncbi.nlm.nih.gov/pubmed/29551903
http://dx.doi.org/10.2147/OTT.S152613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843137/
https://www.ncbi.nlm.nih.gov/pubmed/29551903
http://dx.doi.org/10.2147/OTT.S152613

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