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Anti-TNFα therapy in IBD alters brain activity reflecting visceral sensory function and cognitive-affective biases
BACKGROUND: In inflammatory bowel disease (IBD), immune activation with increased circulating TNF-α is linked to the intensity of gastrointestinal symptoms and depression or anxiety. A central feature of depression is cognitive biases linked to negative attributions about self, the world and the fut...
Autores principales: | Gray, Marcus A., Chao, Che-yung, Staudacher, Heidi M., Kolosky, Natasha A., Talley, Nicholas J., Holtmann, Gerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843226/ https://www.ncbi.nlm.nih.gov/pubmed/29518097 http://dx.doi.org/10.1371/journal.pone.0193542 |
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