Cargando…

Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model

Breast cancer is the most common malignancy in women of the Western world. Doxorubicin (DOX) continues to be used extensively to treat early-stage or node-positive breast cancer, human epidermal growth factor receptor-2 (HER2)-positive breast cancer, and metastatic disease. We have previously demons...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bose, Chhanda, Awasthi, Sanjay, Sharma, Rajendra, Beneš, Helen, Hauer-Jensen, Martin, Boerma, Marjan, Singh, Sharda P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843244/ https://www.ncbi.nlm.nih.gov/pubmed/29518137 http://dx.doi.org/10.1371/journal.pone.0193918

Ejemplares similares

Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice
por: Jun, Se-Ran, et al.
Publicado: (2020)

Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
por: Bose, Chhanda, et al.
Publicado: (2020)

Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells
por: Bose, Chhanda, et al.
Publicado: (2021)

Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects
por: Calcabrini, Cinzia, et al.
Publicado: (2020)

Hydropersulfides (RSSH) attenuate doxorubicin-induced cardiotoxicity while boosting its anticancer action
por: Pharoah, Blaze M., et al.
Publicado: (2023)

Rlip Protein: A Potential Target for COVID-19
por: Kopel, Jonathan, et al.
Publicado: (2022)

R-(-)-carvone Attenuated Doxorubicin Induced Cardiotoxicity In Vivo and Potentiated Its Anticancer Toxicity In Vitro
por: Abbas, Manal Mohammad, et al.
Publicado: (2020)

Telomerase therapy attenuates cardiotoxic effects of doxorubicin
por: Chatterjee, Shambhabi, et al.
Publicado: (2021)

Didymin attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress
por: Chen, Rongchang, et al.
Publicado: (2021)

Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity
por: Sonowal, Himangshu, et al.
Publicado: (2017)

Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity
por: Rephaeli, A, et al.
Publicado: (2007)

Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels
por: Hindle, Ashly, et al.
Publicado: (2022)

Attenuation of Doxorubicin-Induced Cardiotoxicity by mdivi-1: A Mitochondrial Division/Mitophagy Inhibitor
por: Gharanei, Mayel, et al.
Publicado: (2013)

Metformin and Dapagliflozin Attenuate Doxorubicin-Induced Acute Cardiotoxicity in Wistar Rats: An Electrocardiographic, Biochemical, and Histopathological Approach
por: Satyam, Shakta Mani, et al.
Publicado: (2023)

Activation of the MET receptor attenuates doxorubicin‐induced cardiotoxicity in vivo and in vitro
por: Gallo, Simona, et al.
Publicado: (2020)

Melatonin attenuates doxorubicin‐induced cardiotoxicity through preservation of YAP expression
por: Li, Hai‐ru, et al.
Publicado: (2020)

Luteolin Attenuates Doxorubicin-Induced Cardiotoxicity Through Promoting Mitochondrial Autophagy
por: Xu, Haixia, et al.
Publicado: (2020)

Huaier Polysaccharide Attenuates Doxorubicin-Induced Acute Cardiotoxicity by Regulating Ferroptosis
por: Ma, X., et al.
Publicado: (2022)

Lady’s Bedstraw as a Powerful Antioxidant for Attenuation of Doxorubicin-Induced Cardiotoxicity
por: Bradic, Jovana, et al.
Publicado: (2023)

Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia
por: Sharma, Poonam, et al.
Publicado: (2021)

INKing the Cardiotoxicity Out of Doxorubicin
por: Guo, Zhen, et al.
Publicado: (2023)

Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression
por: Xu, Fan, et al.
Publicado: (2017)

Methyl Gallate Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress
por: Ahmed, Akheruz Zaman, et al.
Publicado: (2021)

Doxycycline Attenuates Doxorubicin-Induced Cardiotoxicity by Improving Myocardial Energy Metabolism in Rats
por: Dantas, Danielle, et al.
Publicado: (2022)

Creatine and Resistance Training: A Combined Approach to Attenuate Doxorubicin-Induced Cardiotoxicity
por: Law, David, et al.
Publicado: (2023)

Dendrimer-doxorubicin conjugates exhibit improved anticancer activity and reduce doxorubicin-induced cardiotoxicity in a murine hepatocellular carcinoma model
por: Kuruvilla, Sibu P., et al.
Publicado: (2017)

Schisandrin B Prevents Doxorubicin-Induced Chronic Cardiotoxicity and Enhances Its Anticancer Activity In Vivo
por: Xu, Yang, et al.
Publicado: (2011)

Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy
por: Li, Lan, et al.
Publicado: (2017)

Cardiotoxicity of Anticancer Therapeutics
por: Dong, Jerry, et al.
Publicado: (2018)

Protein-encapsulated doxorubicin reduces cardiotoxicity in hiPSC-cardiomyocytes and cardiac spheroids while maintaining anticancer efficacy
por: Arzt, Madelyn, et al.
Publicado: (2023)

Editorial: Cardiotoxicity induced by radiotherapy and/or chemotherapy after cancer treatment
por: Boerma, Marjan, et al.
Publicado: (2022)

Doxorubicin-induced cardiotoxicity in adult Indian patients on chemotherapy
por: Khattry, Navin, et al.
Publicado: (2009)

Demystifying the Relationship Between Metformin, AMPK, and Doxorubicin Cardiotoxicity
por: Singh, Manrose, et al.
Publicado: (2022)

Ferric Carboxymaltose-Mediated Attenuation of Doxorubicin-Induced Cardiotoxicity in an Iron Deficiency Rat Model
por: Toblli, Jorge Eduardo, et al.
Publicado: (2014)

CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression
por: Tscheschner, Henrike, et al.
Publicado: (2019)

Irvingia gabonensis Seed Extract: An Effective Attenuator of Doxorubicin-Mediated Cardiotoxicity in Wistar Rats
por: Olorundare, Olufunke, et al.
Publicado: (2020)

Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity
por: Hu, Can, et al.
Publicado: (2020)

Taiwanese and Japanese yam (Dioscorea spp.) extracts attenuate doxorubicin-induced cardiotoxicity in mice
por: Chen, Chih-Tai, et al.
Publicado: (2016)

Correction: Schisandrin B Prevents Doxorubicin-Induced Chronic Cardiotoxicity and Enhances Its Anticancer Activity In Vivo
por: Xu, Yang, et al.
Publicado: (2012)

Role of acetylation in doxorubicin-induced cardiotoxicity
por: Li, Daisong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kbrpmgtbg03dkvs8q8naab7bks