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Expression of PD-1 and Tim-3 markers of T-cell exhaustion is associated with CD4 dynamics during the course of untreated and treated HIV infection

INTRODUCTION: T-cell exhaustion has been involved in the pathogenesis of HIV infection. We have longitudinally analyzed PD1 and Tim3 surrogate markers of T-cells exhaustion, in parallel with other markers of HIV progression, and its potential association with CD4 changes in treated and untreated inf...

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Detalles Bibliográficos
Autores principales:	Rallón, Norma, García, Marcial, García-Samaniego, Javier, Cabello, Alfonso, Álvarez, Beatriz, Restrepo, Clara, Nistal, Sara, Górgolas, Miguel, Benito, José M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843247/ https://www.ncbi.nlm.nih.gov/pubmed/29518102 http://dx.doi.org/10.1371/journal.pone.0193829

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