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Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery
Due to toxicity and compliance issues and the emergence of resistance to current medications new drugs for the treatment of Human African Trypanosomiasis are needed. A potential approach to developing novel anti-trypanosomal drugs is by inhibition of the 6-oxopurine salvage pathways which synthesise...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843355/ https://www.ncbi.nlm.nih.gov/pubmed/29481567 http://dx.doi.org/10.1371/journal.pntd.0006301 |