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Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis

The maintenance of the intracellular level of amino acids is crucial for cellular homeostasis. This is carried out via the regulation of both the influx from the extracellular environment and the recycling of intracellular resources. Since epidermal growth factor receptor (EGFR)-tyrosine kinase inhi...

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Detalles Bibliográficos
Autores principales:	Saito, Yu, Moriya, Shota, Kazama, Hiromi, Hirasawa, Kazuhiro, Miyahara, Kana, Kokuba, Hiroko, Hino, Hirotsugu, Kikuchi, Hiroyuki, Takano, Naoharu, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843391/ https://www.ncbi.nlm.nih.gov/pubmed/29484439 http://dx.doi.org/10.3892/ijo.2018.4282

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