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Ultrasensitive Automated RNA in situ Hybridization for Kappa and Lambda Light Chain mRNA Detects B-cell Clonality in Tissue Biopsies with Performance Comparable or Superior to Flow Cytometry

The assessment of B-cell clonality is a critical component of the evaluation of suspected lymphoproliferative disorders, but analysis from formalin fixed paraffin embedded tissues can be challenging if fresh tissue is not available for flow cytometry. Immunohistochemical and conventional bright fiel...

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Detalles Bibliográficos
Autores principales:	Guo, Ling, Wang, Zhen, Anderson, Courtney M., Doolittle, Emerald, Kernag, Siobhan, Cotta, Claudiu V., Ondrejka, Sarah L., Ma, Xiao-Jun, Cook, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843495/ https://www.ncbi.nlm.nih.gov/pubmed/29052600 http://dx.doi.org/10.1038/modpathol.2017.142

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