An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm

Thoracic aortic aneurysm (TAA) has been associated with mutations affecting members of the TGF-β signaling pathway, or components and regulators of the vascular smooth muscle cell (VSMC) actomyosin cytoskeleton. Although both clinical groups present similar phenotypes, the existence of potential com...

Descripción completa

Detalles Bibliográficos
Autores principales: Lino Cardenas, Christian L., Kessinger, Chase W., Cheng, Yisha, MacDonald, Carolyn, MacGillivray, Thomas, Ghoshhajra, Brian, Huleihel, Luai, Nuri, Saifar, Yeri, Ashish S., Jaffer, Farouc A., Kaminski, Naftali, Ellinor, Patrick, Weintraub, Neal L., Malhotra, Rajeev, Isselbacher, Eric M., Lindsay, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843596/
https://www.ncbi.nlm.nih.gov/pubmed/29520069
http://dx.doi.org/10.1038/s41467-018-03394-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843596/
https://www.ncbi.nlm.nih.gov/pubmed/29520069
http://dx.doi.org/10.1038/s41467-018-03394-7

Ejemplares similares