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An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm
Thoracic aortic aneurysm (TAA) has been associated with mutations affecting members of the TGF-β signaling pathway, or components and regulators of the vascular smooth muscle cell (VSMC) actomyosin cytoskeleton. Although both clinical groups present similar phenotypes, the existence of potential com...
Autores principales: | Lino Cardenas, Christian L., Kessinger, Chase W., Cheng, Yisha, MacDonald, Carolyn, MacGillivray, Thomas, Ghoshhajra, Brian, Huleihel, Luai, Nuri, Saifar, Yeri, Ashish S., Jaffer, Farouc A., Kaminski, Naftali, Ellinor, Patrick, Weintraub, Neal L., Malhotra, Rajeev, Isselbacher, Eric M., Lindsay, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843596/ https://www.ncbi.nlm.nih.gov/pubmed/29520069 http://dx.doi.org/10.1038/s41467-018-03394-7 |
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