Cargando…

Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture

Background: Nucleus pulposus (NP) cell apoptosis is a typical feature within the degenerative disc. High magnitude compression significantly promotes NP cell apoptosis. Several studies have indicated that resveratrol has protective effects on disc cell’s normal biology. Objective: The present study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zhiwen, Wen, Feng, He, Chengjian, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843752/ https://www.ncbi.nlm.nih.gov/pubmed/29439139 http://dx.doi.org/10.1042/BSR20171703

Ejemplares similares

Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture
por: Han, Xiaorui, et al.
Publicado: (2017)

The response of nucleus pulposus cell senescence to static and dynamic compressions in a disc organ culture
por: Shi, Jianmin, et al.
Publicado: (2018)

Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence in vitro
por: Li, Xiaoming, et al.
Publicado: (2019)

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
por: Wang, Weiheng, et al.
Publicado: (2018)

Effect of Static Load on the Nucleus Pulposus of Rabbit Intervertebral Disc Motion Segment in an Organ Culture
por: Zhan, Jia-Wen, et al.
Publicado: (2016)

Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture
por: Pang, Lianglong, et al.
Publicado: (2017)

Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway
por: Wang, Wenping, et al.
Publicado: (2018)

Nucleus pulposus cell senescence is alleviated by resveratrol through regulating the ROS/NF-κB pathway under high-magnitude compression
por: Jiang, Yanhai, et al.
Publicado: (2018)

Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS
por: Li, Kang, et al.
Publicado: (2018)

Protective effects of resveratrol on autologous nucleus pulposus model of radiculopathy
por: Lin, Bin, et al.
Publicado: (2016)

Effect of Static Load on the Nucleus Pulposus of Rabbit Intervertebral Disc Motion Segment in Ex vivo Organ Culture
por: Zhu, Li-Guo, et al.
Publicado: (2016)

Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008)

Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
por: Rajasekaran, Shanmuganathan, et al.
Publicado: (2020)

N-cadherin attenuates nucleus pulposus cell senescence under high-magnitude compression
por: Niu, Ming, et al.
Publicado: (2018)

Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway
por: Jiang, Yanhai, et al.
Publicado: (2019)

Cyanidin attenuates the apoptosis of rat nucleus pulposus cells and the degeneration of intervertebral disc via the JAK2/STAT3 signal pathway in vitro and in vivo
por: Bai, Xiaoliang, et al.
Publicado: (2022)

Calcium Phosphate Cement Causes Nucleus Pulposus Cell Degeneration through the ERK Signaling Pathway
por: Zhou, Quan, et al.
Publicado: (2020)

Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway
por: Chen, Sheng, et al.
Publicado: (2017)

Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo
por: Chen, Deheng, et al.
Publicado: (2016)

Taurine attenuates ER stress-associated apoptosis and catabolism in nucleus pulposus cells
por: Yang, Liuxie, et al.
Publicado: (2022)

Current Perspectives on Nucleus Pulposus Fibrosis in Disc Degeneration and Repair
por: Sun, Yi, et al.
Publicado: (2022)

Static compression down-regulates N-cadherin expression and facilitates loss of cell phenotype of nucleus pulposus cells in a disc perfusion culture
por: Zhou, Haibo, et al.
Publicado: (2018)

Grape seed extract inhibits nucleus pulposus cell apoptosis and attenuates annular puncture induced intervertebral disc degeneration in rabbit model
por: B., Ogunlade, et al.
Publicado: (2020)

Regenerative and Immunogenic Characteristics of Cultured Nucleus Pulposus Cells from Human Cervical Intervertebral Discs
por: Stich, Stefan, et al.
Publicado: (2015)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs
por: Feng, Xu, et al.
Publicado: (2018)

HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3
por: Hu, Binwu, et al.
Publicado: (2022)

CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3β Pathway
por: Du, Jiacheng, et al.
Publicado: (2022)

Overexpression of Aquaporin-3 Alleviates Hyperosmolarity-Induced Nucleus Pulposus Cell Apoptosis via Regulating the ERK1/2 Pathway
por: Zhang, Zetong, et al.
Publicado: (2022)

SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells
por: Jiang, Wei, et al.
Publicado: (2014)

Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration
por: Zheng, Zengming, et al.
Publicado: (2018)

Mechanism of Long Noncoding RNA HOTAIR in Nucleus Pulposus Cell Autophagy and Apoptosis in Intervertebral Disc Degeneration
por: Zhang, Shujun, et al.
Publicado: (2022)

Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis
por: Zhang, Xiao-Bo, et al.
Publicado: (2022)

Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells
por: Chen, Chang‐chun, et al.
Publicado: (2020)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2018)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2019)

Osteogenic protein-1 attenuates nucleus pulposus cell apoptosis through activating the PI3K/Akt/mTOR pathway in a hyperosmotic culture
por: Yang, Yan, et al.
Publicado: (2018)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
por: Sakai, Daisuke, et al.
Publicado: (2012)

Changes in the Molecular Phenotype of Nucleus Pulposus Cells with Intervertebral Disc Aging
por: Tang, Xinyan, et al.
Publicado: (2012)

Characterisation of porous knitted titanium for replacement of intervertebral disc nucleus pulposus
por: Tendulkar, Gauri, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c7i9gns6p0v6stigtodioihtfa