(44)Sc for labeling of DOTA- and NODAGA-functionalized peptides: preclinical in vitro and in vivo investigations

BACKGROUND: Recently, (44)Sc (T(1/2) = 3.97 h, Eβ(+) (av) = 632 keV, I = 94.3 %) has emerged as an attractive radiometal candidate for PET imaging using DOTA-functionalized biomolecules. The aim of this study was to investigate the potential of using NODAGA for the coordination of (44)Sc. Two pairs...

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Detalles Bibliográficos
Autores principales: Domnanich, Katharina A., Müller, Cristina, Farkas, Renata, Schmid, Raffaella M., Ponsard, Bernard, Schibli, Roger, Türler, Andreas, van der Meulen, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843811/
https://www.ncbi.nlm.nih.gov/pubmed/29564385
http://dx.doi.org/10.1186/s41181-016-0013-5

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