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Preclinical validations of [(18)F]FPyPEGCBT-c(RGDfK): a (18)F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis
BACKGROUND: α(V)β(3), α(V)β(5) and α(5)β(1) integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they have been selected as promising therapeutic targets. Positron emission tomography (PET) is providing a unique non-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843817/ https://www.ncbi.nlm.nih.gov/pubmed/29564392 http://dx.doi.org/10.1186/s41181-016-0019-z |