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Comparison of the relative importance of vascular and plasma drug concentrations to the hypotensive effect of telmisartan in rats
INTRODUCTION: To clarify the importance of the vascular concentration of an angiotensin II receptor blocker (ARB) to its hypotensive effect, the relationships between the drug concentrations in plasma and vascular tissues and the hypotensive effect after administration of an ARB were compared. MATER...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843848/ https://www.ncbi.nlm.nih.gov/pubmed/27009286 http://dx.doi.org/10.1177/1470320316633895 |