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JAM-A as a prognostic factor and new therapeutic target in multiple myeloma
Cell adhesion in the multiple myeloma (MM) microenvironment has been recognized as a major mechanism of MM cell survival and the development of drug resistance. Here we addressed the hypothesis that the protein junctional adhesion molecule-A (JAM-A) may represent a novel target and a clinical biomar...
Autores principales: | Solimando, A G, Brandl, A, Mattenheimer, K, Graf, C, Ritz, M, Ruckdeschel, A, Stühmer, T, Mokhtari, Z, Rudelius, M, Dotterweich, J, Bittrich, M, Desantis, V, Ebert, R, Trerotoli, P, Frassanito, M A, Rosenwald, A, Vacca, A, Einsele, H, Jakob, F, Beilhack, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843918/ https://www.ncbi.nlm.nih.gov/pubmed/29064484 http://dx.doi.org/10.1038/leu.2017.287 |
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