Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes

The development of extracellular vesicles (EV) for therapeutic applications is contingent upon the establishment of reproducible, scalable, and high-throughput methods for the production and purification of clinical grade EV. Methods including ultracentrifugation (U/C), ultrafiltration, immunoprecip...

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Detalles Bibliográficos
Autores principales: Watson, Dionysios C., Yung, Bryant C., Bergamaschi, Cristina, Chowdhury, Bhabadeb, Bear, Jenifer, Stellas, Dimitris, Morales-Kastresana, Aizea, Jones, Jennifer C., Felber, Barbara K., Chen, Xiaoyuan, Pavlakis, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844027/
https://www.ncbi.nlm.nih.gov/pubmed/29535850
http://dx.doi.org/10.1080/20013078.2018.1442088

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