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Glutathione S-transferase M1 and T1 polymorphisms and the risk of mild hepatotoxicity induced by carbamazepine in a tunisian population study

BACKGROUND: The aim of this study was to evaluate whether the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) null alleles may contribute to carbamazepine-induced hepatotoxicity. METHODS: A cross-sectional prospective study was conducted to identify the frequency distribution of GSTM1 and GSTT1...

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Detalles Bibliográficos
Autores principales:	Chbili, Chahra, Hassine, Anis, Fathallah, Neila, Nouira, Manel, Naija, Salma, Ben Ammou, Sofiene, Saguem, Saad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844121/ https://www.ncbi.nlm.nih.gov/pubmed/29523098 http://dx.doi.org/10.1186/s12883-018-1013-8

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