Cargando…
The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae
CAG/CTG trinucleotide repeats are unstable sequences that are difficult to replicate, repair, and transcribe due to their structure-forming nature. CAG repeats strongly position nucleosomes; however, little is known about the chromatin remodeling needed to prevent repeat instability. In a Saccharomy...
Autores principales: | Koch, Melissa R., House, Nealia C. M., Cosetta, Casey M., Jong, Robyn M., Salomon, Christelle G., Joyce, Cailin E., Philips, Elliot A., Su, Xiaofeng A., Freudenreich, Catherine H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844344/ https://www.ncbi.nlm.nih.gov/pubmed/29305386 http://dx.doi.org/10.1534/genetics.117.300529 |
Ejemplares similares
-
Chromatin modifications and DNA repair: beyond double-strand breaks
por: House, Nealia C. M., et al.
Publicado: (2014) -
The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism
por: Parnell, Timothy J, et al.
Publicado: (2015) -
Expanded CAG/CTG Repeat DNA Induces a Checkpoint Response That Impacts Cell Proliferation in Saccharomyces cerevisiae
por: Sundararajan, Rangapriya, et al.
Publicado: (2011) -
Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126
por: House, Nealia CM, et al.
Publicado: (2019) -
Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange
por: Smolle, Michaela, et al.
Publicado: (2012)