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Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy
During the last decade, our understanding of cancer cell signaling networks has significantly improved, leading to the development of various targeted therapies that have elicited profound but, unfortunately, short-lived responses. This is, in part, due to the fact that these targeted therapies igno...
Autores principales: | Kim, Eunjung, Kim, Jae-Young, Smith, Matthew A., Haura, Eric B., Anderson, Alexander R. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844524/ https://www.ncbi.nlm.nih.gov/pubmed/29522507 http://dx.doi.org/10.1371/journal.pbio.2002930 |
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