NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients

BACKGROUND: Macrophages play a crucial role in the interaction between tumor and immune system, and iNOS is known as a surrogate marker of M1 macrophages activation. The goal of the study was to investigate the role of iNOS polymorphisms as prognostic marker in mCRC patients. MATERIALS AND METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Schirripa, Marta, Zhang, Wu, Yang, Dongyun, Cao, Shu, Okazaki, Satoshi, Loupakis, Fotios, Berger, Martin D., Ning, Yan, Miyamoto, Yuji, Suenaga, Mitsukuni, Alberti, Giulia, West, Jordan D., Lonardi, Sara, Khoukaz, Taline, Bergamo, Francesca, Battaglin, Francesca, Antoniotti, Carlotta, Falcone, Alfredo, Stintzing, Sebastian, Heinemann, Volker, Lenz, Heinz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844536/
https://www.ncbi.nlm.nih.gov/pubmed/29522543
http://dx.doi.org/10.1371/journal.pone.0193640

Ejemplares similares

Ejemplares similares