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Niemann-Pick type C2 protein supplementation in experimental non-alcoholic fatty liver disease

BACKGROUND AND AIMS: Hepatic cholesterol deposition drives inflammation and fibrosis in non-alcoholic steatohepatitis (NASH). The Niemann-Pick type C2 (NPC2) protein plays an important role in regulating intracellular cholesterol trafficking and homeostasis. We hypothesized that intravenous NPC2 sup...

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Detalles Bibliográficos
Autores principales:	Christensen, Claus Uhrenholt, Glavind, Emilie, Thomsen, Karen Louise, Kim, Yong Ook, Heebøll, Sara, Schuppan, Detlef, Hamilton-Dutoit, Stephen, Würtz Heegaard, Christian, Grønbæk, Henning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844539/ https://www.ncbi.nlm.nih.gov/pubmed/29522534 http://dx.doi.org/10.1371/journal.pone.0192728

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