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Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes

Type 1 diabetes (T1D) is caused by the autoimmune destruction of the insulin-producing pancreatic beta cells. While the role of adaptive immunity has been extensively studied, the role of innate immune responses and particularly of Toll- like Receptor (TLR) signaling in T1D remains poorly understood...

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Detalles Bibliográficos
Autores principales:	Androulidaki, Ariadne, Wachsmuth, Laurens, Polykratis, Apostolos, Pasparakis, Manolis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844544/ https://www.ncbi.nlm.nih.gov/pubmed/29522531 http://dx.doi.org/10.1371/journal.pone.0194048

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