Cargando…

Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes

DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damage, which cause either single- or double-strand breaks in the DNA. Here, we propose a strategy for the functional study of single nucleotide polymorphisms (SNPs) in the human DNA repair genes XPD/ERCC2, RAD18,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Changshin, Yang, Jinmo, Jeong, Su-Hyun, Kim, Hayoung, Park, Geun-hee, Shin, Hwa Beom, Ro, MyungJa, Kim, Kyoung-Yeon, Park, YoungJoon, Kim, Keun Pil, Kwack, KyuBum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844570/ https://www.ncbi.nlm.nih.gov/pubmed/29522548 http://dx.doi.org/10.1371/journal.pone.0193823

Ejemplares similares

Functional Validation of Rare Human Genetic Variants Involved in Homologous Recombination Using Saccharomyces cerevisiae
por: Lee, Min-Soo, et al.
Publicado: (2015)

Identification of potential causal variants for premature ovarian failure by whole exome sequencing
por: Jin, Haengun, et al.
Publicado: (2020)

Role of RGMc as a Neogenin Ligand in Follicular Development in the Ovary
por: Kim, Yu Jin, et al.
Publicado: (2021)

Association of an APBA3 Missense Variant with Risk of Premature Ovarian Failure in the Korean Female Population
por: Park, JeongMan, et al.
Publicado: (2020)

Upregulation of the NLRC4 inflammasome contributes to poor prognosis in glioma patients
por: Lim, Jaejoon, et al.
Publicado: (2019)

CeRNA Network Analysis Representing Characteristics of Different Tumor Environments Based on 1p/19q Codeletion in Oligodendrogliomas
por: Ahn, Ju Won, et al.
Publicado: (2020)

Correction: Ahn, J.W., et al. CeRNA Network Analysis Representing Characteristics of Different Tumor Environments Based on 1p/19q Codeletion in Oligodendrogliomas. Cancers 2020, 12, 2543
por: Ahn, Ju Won, et al.
Publicado: (2021)

Interaction between thyroglobulin and ADAMTS16 in premature ovarian failure
por: Pyun, Jung-A, et al.
Publicado: (2014)

Mediatory roles of leukotriene B(4) receptors in LPS-induced endotoxic shock
por: Kwon, Sun-Young, et al.
Publicado: (2019)

Leukotriene B(4) receptors mediate the production of IL‐17, thus contributing to neutrophil‐dominant asthmatic airway inflammation
por: Ro, MyungJa, et al.
Publicado: (2019)

Autologous adoptive immune-cell therapy elicited a durable response with enhanced immune reaction signatures in patients with recurrent glioblastoma: An open label, phase I/IIa trial
por: Lim, Jaejoon, et al.
Publicado: (2021)

Contributory Role of BLT2 in the Production of Proinflammatory Cytokines in Cecal Ligation and Puncture-Induced Sepsis
por: Park, Donghwan, et al.
Publicado: (2021)

Downregulation of LOC441461 Promotes Cell Growth and Motility in Human Gastric Cancer
por: Lee, Sang-soo, et al.
Publicado: (2022)

Sex-specific differences in the association of a common aldehyde dehydrogenase 2 gene polymorphism and alcohol consumption with stroke risk in a Korean population: a prospective cohort study
por: Shin, Chol, et al.
Publicado: (2015)

Role of Nuclear-Receptor-Related 1 in the Synergistic Neuroprotective Effect of Umbilical Cord Blood and Erythropoietin Combination Therapy in Hypoxic Ischemic Encephalopathy
por: Choi, Joo-Wan, et al.
Publicado: (2022)

Diplotyper: diplotype-based association analysis
por: Kim, Sunshin, et al.
Publicado: (2013)

Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy in Refractory Solid Tumors at a Korean Institution
por: Park, Hyung Soon, et al.
Publicado: (2016)

A Disintegrin and Metalloproteinase 9 (ADAM9) in Advanced Hepatocellular Carcinoma and Their Role as a Biomarker During Hepatocellular Carcinoma Immunotherapy
por: Oh, Sooyeon, et al.
Publicado: (2020)

Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate
por: Jin, Li Hua, et al.
Publicado: (2017)

Nitric oxide synthase Type II expression by different cell types in MHV-JHM encephalitis suggests distinct roles for nitric oxide in acute versus persistent virus infection
por: Grzybicki, Dana M, et al.
Publicado: (1997)

Natural Killer Cell Therapy: A New Treatment Paradigm for Solid Tumors
por: Oh, Sooyeon, et al.
Publicado: (2019)

Vitamin D and Exercise Are Major Determinants of Natural Killer Cell Activity, Which Is Age- and Gender-Specific
por: Oh, Sooyeon, et al.
Publicado: (2021)

Association between Interferon-Inducible Protein 6 (IFI6) Polymorphisms and Hepatitis B Virus Clearance
por: Park, Geun-Hee, et al.
Publicado: (2013)

Protective Effects of Galla Rhois, the Excrescence Produced by the Sumac Aphid, Schlechtendalia chinensis, on Transient Focal Cerebral Ischemia in the Rat
por: Lee, Kyungjin, et al.
Publicado: (2012)

Ultrasonography Findings in Hereditary Neuropathy with Liability to Pressure Palsies Due to Single-Nucleotide Substitution
por: Kim, Yong Kyun, et al.
Publicado: (2020)

Rice-eating pattern and the risk of metabolic syndrome especially waist circumference in Korean Genome and Epidemiology Study (KoGES)
por: Ahn, Younjhin, et al.
Publicado: (2013)

Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study
por: Pyun, Jung-A, et al.
Publicado: (2012)

Modified Peritoneal Dialysis Catheter Insertion: Comparison with a Conventional Method
por: Lee, Yong Kyu, et al.
Publicado: (2015)

In Silico Evaluation of Natural Compounds for an Acidic Extracellular Environment in Human Breast Cancer
por: Park, YoungJoon, et al.
Publicado: (2021)

A Statistical Analysis of Superior Orbital Fissure Width in Korean Adults using Computed Tomography Scans
por: Park, Yongsik, et al.
Publicado: (2017)

A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells
por: Lee, Jae Yong, et al.
Publicado: (2017)

Changes in the phosphorylation of nucleotide metabolism-associated proteins by leukemia inhibitory factor in mouse embryonic stem cells
por: Song, Hwa-Ryung, et al.
Publicado: (2021)

SET7-mediated TIP60 methylation is essential for DNA double-strand break repair
por: Kim, Song Hyun, et al.
Publicado: (2022)

Cost-Effectiveness of Carotid Endarterectomy versus Carotid Artery Stenting for Treatment of Carotid Artery Stenosis
por: Kim, Jong Hun, et al.
Publicado: (2014)

Dynamic Temporal Change of Cerebral Microbleeds: Long-Term Follow-Up MRI Study
por: Lee, Seung-Hoon, et al.
Publicado: (2011)

Dietary yeast cell wall enhanced intestinal health of broiler chickens by modulating intestinal integrity, immune responses, and microbiota
por: Kyoung, Hyunjin, et al.
Publicado: (2023)

Clinically beneficial continued treatment with gefitinib after asymptomatic progression of lung adenocarcinoma
por: Choi, Hayoung, et al.
Publicado: (2015)

Genome-Wide Analysis of Cyclic Nucleotide-Gated Channel Genes Related to Pollen Development in Rice
por: Lee, Su-Kyoung, et al.
Publicado: (2022)

Physicochemical and Functional Properties of Yeast-Fermented Cabbage
por: Chun, Ahhyeon, et al.
Publicado: (2023)

Single-chip photonic transceiver based on bulk-silicon, as a chip-level photonic I/O platform for optical interconnects
por: Kim, Gyungock, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_soa4tv6ns4q4k78du87irihhkh